What do rattlesnakes eat? Rattlesnakes kill their prey with poison. They feed on a variety of prey like rats, mice, chipmunks and other small animals. Related posts: “He liked to tease and play”. Who is teasing whom? How? How are some of the snakes? Where did the lady find the bear cub? How did she bring it up? How did the book change Think Tank’s opinion about the Earthlings?